AMSは北大発認定スタートアップ企業です

Initial 177Lu Adsorption Experiment and RAVIN CAM Imaging at Hokkaido University Hospital

August 26, 2025
On August 20, 2025, the first clinical-scale adsorption experiment was performed at Hokkaido University Hospital using the installed 177Lu removal system, BSL-177. Concurrently, the adsorption process was evaluated using the 3D radiation visualization camera “RAVIN CAM.”
① Pre-treatment assessment of urine collection bottle

RAVIN CAM detected gamma radiation derived from residual 177Lu present in the collected urine, confirming the baseline activity prior to adsorption.

② Adsorption within the BSL-177 cart

The urine collection bottle was transferred into the BSL-177 cart for adsorption treatment. During operation, no detectable external radiation was observed on RAVIN CAM imaging owing to the six-sided lead shielding integrated within the cart, demonstrating adequate radiological protection.

③ Comparison of pre- and post-treatment urine samples, and evaluation of the adsorption column

Pre-treatment urine samples demonstrated measurable gamma emissions, whereas post-treatment urine samples exhibited no detectable radiation on RAVIN CAM imaging, confirming efficient removal of 177Lu by the BSL-177 system. Additionally, RAVIN CAM visualization confirmed migration and adsorption of 177Lu onto the BSL-177 column, indicating successful radionuclide sequestration.

*Unauthorized copying and replication of the contents of this site, text and images are strictly prohibited.